Researchers are getting closer to successfully developing a drug that mimics the effects of exercise.
At a meeting of the American Chemical Society (ACS), scientists introduced a drug currently under research that contains components that may provide effects equivalent to those of exercising, as reported by Newsweek on March 18.
When exercising, the body metabolizes by activating specialized proteins known as Estrogen-Related Receptors (ERR). There are three types of these receptors: ERRα, ERRβ, and ERRγ. Among them, ERRα is the most crucial protein because it regulates the adaptability of muscles according to the intensity of exercise.
The pill being introduced is named SLU-PP-332. Upon consumption, it activates all three types of ERR, assisting users in achieving a metabolic process similar to that of exercising.
Results from tests on mice indicate that the drug helps enhance muscle fibers, reduces fatigue, and improves endurance. Subsequent research will focus on optimizing the drug’s stability and reducing the risk of toxicity.
The drug being developed can activate metabolism similar to that of exercising. (Photo: Newsweek).
“At least for lazy people like me, we can benefit from this drug,” said Bahaa Elgendy, an anesthesiology professor at the University of Washington School of Medicine and author of the study.
However, he emphasized that this research does not encourage using drugs as a substitute for exercise. This drug is focused on assisting individuals who have lost their mobility due to health issues or enhancing physical activity in the elderly, those with muscle atrophy, or certain diseases.
Elgendy stated that if successful in developing this drug, scientists could create treatments for some of the most challenging diseases, such as neurodegeneration and heart failure.
SLU-PP-332 and other compounds are believed to have potential against conditions such as kidney dysfunction, heart failure, obesity, and Alzheimer’s disease.
