American researchers have discovered the anti-cancer properties of one of the most widely cultivated and consumed mushrooms in the world.
In a study recently published in the medical journal Clinical and Translational Medicine, a team from the City of Hope cancer research organization in the United States demonstrated the anti-cancer potential of Agaricus bisporus extracts.
Agaricus bisporus, also commonly known as button mushroom or white mushroom, is one of the most widely used edible mushrooms.
Agaricus bisporus extract may help combat prostate cancer – (AI Illustration: Anh Thư).
According to Science Alert, like many other tumors, tumors in prostate cancer protect themselves by producing myeloid-derived suppressor cells (MDSC), which prevent the patient’s immune system from attacking the pathogen.
The new study shows that extracts from the button mushroom can break through this shield.
In a previous Phase I clinical trial, researchers at City of Hope found promising signs that white mushroom extracts could help control prostate cancer.
Some volunteers even experienced a reduction in circulating MDSC levels.
After several months of taking Agaricus bisporus extract supplements twice a day, some participants had reduced prostate cancer markers in their blood to undetectable levels.
Recently, researchers conducted a parallel study on mice and a Phase II clinical trial to explore the mechanisms behind the observed effects.
In mice with prostate cancer, mushroom extracts significantly slowed tumor growth and extended lifespan.
In the ongoing Phase II clinical trial, patients receiving Agaricus bisporus extract showed lower levels of MDSC and higher counts of anti-tumor immune cells.
However, this does not mean that button mushrooms can replace medication.
Instead, they may be used as a safe nutritional approach to support other treatment therapies by enhancing immune system strength and restraining the disease.
Additionally, research steps indicate that consuming this type of mushroom may also help prevent prostate cancer in healthy individuals.
Essentially, button mushrooms, like other mushrooms, are rich in soluble fiber, protein, lipids, and phytochemicals, all of which can be toxic to cancer cells.
The authors noted that the research is still ongoing to develop an appropriate nutritional therapy as an adjunctive intervention for cancer patients.
Nonetheless, it is definitely beneficial for men to occasionally include fresh button mushrooms in their diet starting now.
