A 22-Year-Old Girl Born Without a Uterus and a 4-Year-Old Girl with Congenital Loss of Retinoblastoma Control—Both Found to Have Abnormal Chromosome Structures in China
Scientists at the Healthy Reproductive Technology Center of the Family Planning Research Institute in Guangdong Province, China, have discovered 39 cases of individuals with unusual chromosome structures, which are believed to be unprecedented globally.
In the case of the 22-year-old woman, tests revealed that she possesses an abnormal chromosome set, leading to the absence of a gene crucial for uterine development. Furthermore, this chromosomal abnormality has also resulted in a pair of male twins having low sperm counts.
Zheng Lixin, the director of the center, stated that these cases have been confirmed by the National Gene Laboratory in Hunan Province.
This finding emerged after the analysis of 5,000 blood samples, raising the total number of documented chromosomal abnormalities in China to 1,838. The discovery of these additional chromosomal anomalies could provide valuable insights for scientists studying genetics and cloning.
Zheng also mentioned that currently, there is no effective treatment for some individuals with genetic disorders and low fertility due to inherited chromosomal abnormalities. However, doctors can offer clinical advice if alerted to the conditions of their patients. For instance, they may recommend artificial insemination to prevent defects in offspring.
Abnormal chromosomes may result from exposure to chemicals, radioactive materials, or viruses. Discovering these abnormalities can also serve as indirect indicators for assessing environmental pollution.
T. An
