The Afternoon Nap: A Biological Response to Lunch
 |
| Image: dreamstime |
Researchers have discovered that sugar in food, also known as glucose, can inhibit brain cells from generating signals that help keep us alert, according to Denis Burdakov from the University of Manchester in the UK.
“It has long been known that both humans and animals can feel sleepier and lethargic after a meal, but the brain signals responsible for this phenomenon have not been well understood,” Burdakov stated. His team found that glucose prevents neurons from producing orexin—tiny proteins that help keep us awake.
“These cells respond to changes in the body’s energy state, synchronizing wakefulness, food-seeking behavior, hormone release, and metabolic rate, to ensure that the brain always receives enough glucose,” Burdakov explained.
Impaired function of orexin-producing cells can lead to narcolepsy and obesity.
“Now we know that glucose inhibits the activity of orexin-producing cells. The results may help explain why we feel sluggish after meals and why it can be hard to sleep when hungry,” Burdakov added.
M.T.
